Finasteride vs Minoxidil: Choosing the Best Hair Loss Treatment for You

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We can expect to lose between 50 and 100 hairs every day. [1] This may seem like a lot of hair, but we don’t tend to notice it because new hair follicles grow back in their place. However, hair follicles can shrink due to aging, genetics and other factors, leading to noticeable patches of hair loss. This condition is calle alopecia, also known as male or female pattern baldness.

Finasteride and Minoxidil are two of the most popular hair loss medications available. Both of these treatments for hair loss are used in the UK and worldwide by individuals who struggle with hair thinning or a receding hairline. While they share the same end goal of combating hair loss for good, both treatments have several differences.

In this blog article, we explain the differences between Finasteride and Minoxidil, including whether they can be used together to help you determine which one is best.

 

What Is The Difference Between Minoxidil and Finasteride?

The main differences between Finasteride and Minoxidil are the way they work and the forms in which they are available. Finasteride is a prescription medication that works by blocking the enzyme responsible for converting testosterone into dihydrotestosterone (DHT). Stopping the production of DHT helps prevent further hair loss and improves hair density and regrowth. Finasteride is available as oral tablets. 

On the other hand, Minoxidil works by increasing the blood flow around hair follicles to stimulate hair growth. Not only does it promote hair follicles to the growth phase, but it also prolongs the hair growth cycle phase, resulting in fuller and longer hair. Minoxidil is available by prescription in oral tablet form and over-the-counter as a topical treatment in the form of a solution or foam which is applied to the affected scalp area.

Are Finasteride and Minoxidil Suitable for Both Men and Women?

Finasteride is specifically for the treatment of male pattern baldness. The causes of hair loss and thinning in women differ from those in men. Therefore, it is not usually prescribed to women with female pattern baldness. Finasteride works by blocking the enzyme that converts testosterone into DHT. The female body produces far less amounts of testosterone and DHT compared to the male body. Therefore, Finasteride won’t help with female pattern baldness. 

Another reason why Finasteride is not suitable for women is because it can be absorbed by the skin and cause serious birth defects if used during pregnancy. It should never be taken by women who are pregnant, may become pregnant or are breastfeeding. [2]

In contrast, Minoxidil can be taken by both men and women who suffer from alopecia. In fact, topical Minoxidil is the only FDA-approved treatment for hair loss in women (female pattern baldness). [3] As it is applied directly to the scalp, it is not intended to affect hormone levels like Finasteride does.

Similar to Finasteride, it is not advised for women to use Minoxidil during pregnancy or breastfeeding. [4]

Minoxidil vs Finasteride: What You Need to Know About Dosage

Like any other medication, instructions must be followed and the right dosage needs to be taken to achieve the best results. The recommended dosage of Finasteride for men is 1mg once a day. 

Generally, Minoxidil is prescribed to men in a 5% solution or foam, whereas women are prescribed a 2% solution or 5% foam. For men, the recommended dosage for 5% solution is 1ml twice daily. The dosage for 5% foam is half a capful twice daily. For women, the usual dosage is 1ml of 2% solution twice daily or half a capful of 5% foam once a day.

Although Minoxidil 5% is an effective hair loss treatment for men and has been used for several years, a higher 6% strength topical spray is also available. Studies show that a small percentage increase is likely to yield better results without a proportionate increase in side effects.[5]

Whether you choose Finasteride or Minoxidil for your hair loss, it is important to check with your healthcare provider before starting treatment to ensure you take the right dosage for your specific needs. Taking the incorrect dosage can cause ineffective results and increase the potential risk of side effects. 

Which One is More Expensive?

Cost can be a main factor for individuals choosing between the two treatments. Finasteride tends to be more expensive because it is a prescription-only medication, whereas Minoxidil can be purchased over the counter. 

On average, high-street pharmacies in the UK charge from £11 to £55 for a 28-tablet box of Finasteride 1mg (4-week supply). At Chemist Click, a 28-tablet box of Finasteride 1mg starts from £13.89. You can expect to pay more for larger quantities. A 168-tablet box of Finasteride 1mg (28-week supply) ranges from £50 to £245, depending on the pharmacy and brand.

Meanwhile, the cost of Minoxidil depends on strength, quantity and brand. The average cost of a 60ml bottle of 2% solution is £12 to £28 and for a 5% solution is £15 to £35. For a 73g can of 5% foam, the average cost can vary from £15 to £40.

What are the Potential Side Effects? 

Minoxidil and Finasteride have distinct side effects associated with their use.

Each treatment has its potential downsides, and our role is to guide you through these complications.

Minoxidil typically causes side effects at the site of application, including:

  • Irritation of the skin
  • General Itching
  • Unwanted hair growth on other areas of the body
  • Redness in the treated area

In rare instances, symptoms can be more severe such as blurred vision or an irregular heartbeat may occur from using Minoxidil.

On the other hand, Finasteride is more likely to cause possible side effects than Minoxidil. This is because Finasteride works by reducing DHF levels in the male body, which can cause side effects such as:

  • Sexual side effects such as erectile dysfunction or reduced sexual desire
  • Swelling and tenderness in the breasts

Although these side effects are uncommon, they can be more serious than those associated with Minoxidil.

Your well-being is our top concern. It’s crucial to monitor for any abnormal symptoms and consult a healthcare provider promptly. Achieving fuller hair should not compromise your overall health.

Finasteride vs Minoxidil: Which Is More Effective for Hair Loss?

The effectiveness of Finasteride versus Minoxidil as a hair loss treatment can hugely depend on the type of hair loss.

In a clinical study, 40 patients were selected to take 1 mg/day of oral Finasteride and 25 patients were chosen to take 5% topical Minoxidil twice a day. After 12 months of treatment, the study found that oral Finasteride and topical Minoxidil were effective and safe in treating mild to severe androgenetic alopecia. However, oral Finasteride appeared to be more effective. [6]

Both treatments are clinically proven to treat alopecia. If the production of DHT is not the cause of hair loss, Finasteride is less likely to help with hair regrowth. If hair loss is caused by other conditions such as female pattern baldness, alopecia areata or telogen effluvium, Minoxidil is likely to be more effective than Finasteride. 

Is It Safe to Take Minoxidil and Finasteride Together?

Research shows that it is relatively safe to use Finasteride and Minoxidil together. This combination may be a good first-line approach for men seeking improvement in hair growth. 

In a comparative study of 450 Chinese patients with male androgenetic alopecia, 160 men were assigned to take Finasteride 1 mg/day, 130 men were assigned to take 5% topical Minoxidil and 160 men were assigned to take combined medication. After 12 months, the study found that men who took the combined medication showed the best efficacy (94.1%), behind Finasteride (80.5%) and Minoxidil (59%). [7]

If you are considering using a combination of oral Finasteride and topical Minoxidil to treat hair loss, please consult with your healthcare provider beforehand to discuss the potential risks and benefits.

Minoxidil vs Finasteride: Which Is the Right Option for You?

If you are suffering from male pattern baldness, Finasteride is likely to be the best way to stop hair loss. Otherwise, if you are suffering from female pattern baldness, alopecia areata or telogen effluvium, then Minoxidil may be more suitable for your head of hair. You should always consult with your healthcare provider before taking either medication to discuss your hair loss condition, medical history and other specific factors to find the right treatment plan for you. 

Sources

  1. NHS. (2024). Hair loss. Retrieved on 14th August 2024, from: https://www.nhs.uk/conditions/hair-loss/
  2. Mayo Clinic (2024). Finasteride (Oral Route). Retrieved on 14th August 2024, from: https://www.mayoclinic.org/drugs-supplements/finasteride-oral-route/description/drg-20063819
  3. National Library of Medicine. (2024). Minoxidil dose response study in female pattern hair loss patients determined to be non-responders to 5% topical minoxidil. Retrieved on 14th August 2024, from: https://pubmed.ncbi.nlm.nih.gov/28078868/
  4. National Library of Medicine. (2024). Minoxidil. Retrieved on 14th August 2024, from: https://www.ncbi.nlm.nih.gov/books/NBK482378/
  5. National Library of Medicine. (2002). A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. Retrieved on 5th September 2024, from: https://pubmed.ncbi.nlm.nih.gov/12196747/
  6. National Library of Medicine. (2024). An open, randomised, comparative study of oral finasteride and 5% topical minoxidil in male androgenetic alopecia. Retrieved on 14th August, from: https://pubmed.ncbi.nlm.nih.gov/15316165/
  7. Wiley Online Library. (2015). Combined treatment with oral finasteride and topical minoxidil in male androgenetic alopecia: a randomised and comparative study in Chinese patients. Retrieved on 14th August 2024, from: https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.12246

Whilst all of our content is written and reviewed by healthcare professionals, it is not intended to be substituted for or used as medical advice. If you have any questions or concerns about your health, please speak to your doctor.