Tadalafil Tablets
2.5mg / 5mg / 10mg / 20mg

About Tadalafil

Buy Tadalafil Online in the UK

You can buy tadalafil online today from Chemist Click, for a fast and discreet delivery to your door. To receive treatment, complete a free consultation above, for our UK-based team to review.
 

What is Tadalafil (Generic Cialis)?

Tadalafil is a generic medicine used to treat ED. It belongs to the class of drugs known as PDE5 inhibitors. It contains the same active ingredient as Cialis but is available as a non-branded version, often referred to as "generic Cialis."

Tadalafil comes in two different variations:

• Tadalafil 2.5mg & 5mg - Known as Tadalafil Once Daily Tablets
• Tadalafil 10mg & 20mg - Known as Tadalafil 36-hour

Tadalafil Benefits

Tadalafil receives good reviews from users, proving to be a popular and successful treatment amongst many men. Studies show that it is highly effective in treating ED, with a relatively low side effect profile. It also offers the advantage of a daily tablet which is an attractive option for those who have sex regularly, or don’t like the idea of planning sexual activities. 

The medication also has a long half-life of around 17 hours. This is the time that it takes for the drug to leave your system. This means that missing the odd dose should not have a negative impact on your sex life.

Overall, tadalafil offers a flexible and effective option for men dealing with erectile dysfunction, promoting a more spontaneous and satisfying sexual experience when used appropriately and under the guidance of a healthcare professional.
 

How Does Tadalafil Work?

Tadalafil works by encouraging blood flow to the penis during sexual stimulation. This helps users to achieve and maintain an erection.

Important note: Tadalafil will only work where there is sexual stimulation. It will not help to increase sexual desire.

Tadalafil Dosage Instructions

Which Strength of Tadalafil is Best For Me?

Tadalafil 2.5mg (Daily Dose)

2.5mg is the recommended starting dose for tadalafil daily.

The chances of experiencing side effects are lower with the 2.5mg strength. If you have not been successful after 8 separate attempts, you should speak to your doctor or pharmacist about increasing the strength to 5mg.
 

Tadalafil 5mg (Daily Dose)

5mg is the higher strength daily tablet, usually prescribed for those who have not experienced the desired effects with the 2.5mg tablets.

Your doctor or pharmacist may wish to start you off using the 5mg tablets. This can depend on factors such as your BMI and age.
 

Tadalafil 10mg (When Required Dose)

Tadalafil 10mg is the starting dose for those wishing to take tadalafil on a “when required” basis.

The chances of experiencing side effects are lower with the 10mg strength, in comparison with 20mg. You should only look to increase the dose if you have been unsuccessful after 8 separate attempts. If the 10mg tablets are working well for you, a dose increase is not necessary. This will increase the chances of experiencing side effects, and there are no proven benefits that an erection will be of a better quality if you increase the dose without the need to.
 

Tadalafil 20mg (When Required Dose)

Tadalafil 20mg tablets are the next step up from 10mg.

Your doctor or pharmacist may prescribe you with the 20mg strength if you have had limited success with the 10mg tablets. If you have tried the 20mg strength on 8 separate occasions with limited success, you may wish to try an alternative ED tablet.
 

What is the Maximum Dose of Tadalafil in 24 hours?

The maximum dose of tadalafil is 20mg within 24 hours. This should be as a single dose, and not in divided doses. If you have limited success with a lower dose, do not take more to make up 20mg. If you have been advised by your doctor or pharmacist to increase your dose to tadalafil 20mg, wait until the following day if you have already taken a tablet. 

Never take more than one tablet within 24 hours.
 

How To Take Tadalafil for Erectile Dysfunction

If you are taking the 2.5mg or 5mg daily dose tablets, take one tablet around the same time each day. The time of day does not impact the effectiveness of treatment.

If you are taking the 10mg or 20mg tablets, take one tablet at least 30 minutes before sexual activity. 

You should take tadalafil with a glass of water. Food does not usually affect the absorption of the tablet, and neither does moderate amounts of alcohol. However, excess alcohol can negatively impact erections.
 

How Long Does Tadalafil Take to Work?

Tadalafil 20mg and 10mg take around 30 minutes to start working. Food does not usually affect the absorption of the tablets.

It can take around 5 days of consistent use to see the benefits of tadalafil daily (5mg and 2.5mg strengths), which are continuous.
 

How Long Does Tadalafil Last?

Tadalafil 20mg and 10mg are known as the “when required dose”. They have a window of action of up to 36 hours. This allows users to benefit from multiple sexual encounters within the 36-hour timeframe that the drug is effective for.

Tadalafil 5mg and 2.5mg are known as the “daily dose”, as they are taken every day. Both the 5mg and 2.5mg strengths have a continuous window of action, allowing users to benefit from spontaneous sexual activity, without the need for scheduling doses. The effects last for as long as the tablets are taken.

Tadalafil Side Effects

Tadalafil can cause several side effects, as is the case with most medication. Not everyone experiences side effects however. These include:

Common: Affecting up to 10% of users

• Headache
• Muscle pain
• Flushing
• Nasal congestion
• Indigestion
• Uncommon: Affecting up to 1% of users:
• Palpitations
• Chest pain
• Dizziness
• Fatigue
• Eye pain
• High blood pressure
• Low blood pressure
• Nausea
• Skin reactions
• Ringing in the ears
• Vomiting
• Visual disturbances

If you experience any of the following, seek urgent medical assistance:

• Chest pain
• A painful erection and/or one lasting more than 4 hours
• Seizure
• Sudden loss or altered vision
• Signs of a serious allergic reaction such as difficulty breathing, severe skin reactions, or swelling of the lips, eyes, mouth, or throat

You should read the patient information for a full list of side effects. If you experience any side effects, you should inform your doctor or pharmacist, or in serious cases, seek urgent medical assistance. You should always inform us if you have experienced any side effects from taking Sildenafil.
 

Does Tadalafil Have Any Long-Term Side Effects?

There are no known long-term side effects of taking tadalafil. Most of the time, side effects subside after a few hours. If you experience side effects that do not disappear after a few hours, you should seek medical attention. Especially if you have a prolonged erection that lasts for more than 4 hours.
 

Tadalafil Warnings

Warnings and Precautions of Tadalafil

Although tadalafil is generally suitable for most men with erectile dysfunction, this does not mean that everyone can take it. Please read the following warnings before taking tadalafil and also consult your doctor or healthcare provider:

• You should only use tadalafil as prescribed by a healthcare professional.
• Tadalafil should not be taken by women or children.
• You should not take tadalafil if you have certain medication conditions such as kidney or liver problems, certain heart conditions, certain eye conditions, stomach ulcers, bleeding disorders, or an anatomical deformation of the penis. You should always let your doctor or pharmacist know of any medication conditions before taking tadalafil, so that they can assess whether it is safe for you to take.
• Do not take tadalafil if you have a medical condition called angina, or you are taking medication to treat angina (nitrates).
• You should not take tadalafil if you have low blood pressure or uncontrolled high blood pressure.
• You should not take tadalafil if you are allergic to tadalafil, or any of the other ingredients listed in the patient information leaflet.
• You should seek medical attention if you experience a sudden decrease or loss in vision or hearing after taking tadalafil
   

Tadalafil Interactions

Tadalafil is generally safe to take with most medications. You should speak to your doctor before taking tadalafil if you are taking:

• Alpha blockers such as alfuzosin, doxazosin or tamsulosin
• Medication to treat blood pressure
• Any heart medication
• Medication to treat epilepsy
• Antifungal treatment
• Crizotinib, enzalutamide, imatinib, nilotinib, idelalisib prescribed to treat some cancers
• HIV medication
• Erythromycin, clarithromycin, or rifampicin (antibiotics)
• Netupitant or aprepitant prescribed to treat sickness
• Nitrates 
• St John's Wort
• Sapropterin

If you are taking any of these medications, you may still be able to take tadalafil, but your doctor may wish to monitor you, or you may need to leave a gap before taking a tablet.

Tadalafil Ingredients

Active ingredients: Tadalafil

Inactive ingredients: Croscarmellose sodium, lactose monohydrate, sodium lauryl sulfate, hydroxypropyl cellulose, magnesium stearate, microcrystalline.

Whilst the active ingredient will remain the same, the inactive ingredients may differ amongst brands. You should read the tadalafil patient information leaflet supplied with your medication, for a full list of ingredients.

Tadalafil Alternatives

What is the Difference Between Tadalafil and Viagra?

Both tadalafil and Viagra are effective erectile dysfunction tablets and are clinically proven to help treat ED. They have similar success rates.

Both medications do however differ primarily in their effective duration and onset of action. Tadalafil can remain effective for up to 36 hours, significantly longer than the 4-hour duration of Viagra. Additionally, tadalafil can start working within 30 minutes, whereas Viagra typically requires an hour to take effect.

Another advantage of tadalafil is the option for daily dosing, which supports spontaneity in sexual activity, a feature not available with Viagra, which must be taken prior to each sexual encounter.
 

What Is The Difference Between Tadalafil and Sildenafil?

Sildenafil, commonly known as "generic Viagra," typically takes longer to become effective, with effects lasting up to 4 hours. In contrast, tadalafil starts working more quickly and maintains its effectiveness for an extended period.

Both medications generally share similar side effects. However, their primary distinctions lie in the onset speed and duration of effectiveness.

Unlike tadalafil, sildenafil should also be taken on an empty stomach, as food can delay its effect and decrease the levels of the drug in the bloodstream.

Many men prefer tadalafil due to its faster action. Conversely, others opt for sildenafil because of its longstanding presence in the market, which has led to a broader understanding of its effects and side effects. Additionally, sildenafil is typically cheaper than tadalafil, making it a more attractive choice for some.

For more information on the differences between the two, take a look at our guide ‘Sildenafil vs Tadalafil’.

Sources

1. https://www.nhs.uk/medicines/tadalafil/
2. https://bnf.nice.org.uk/drugs/tadalafil/
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643112/